SetBack U

Setback U is an “empathy game” designed to aid the understanding of mental disorders common among college students. It provides players a safe, controlled context in which to experience the frustration and other negative effects associated with such disorders, and suggests ways to manage these emotions in an appropriate manner

Gamification

Gamification is the act of changing human behavior by making activities more enjoyable by making them more game-like. This could be as simple as adding rewards for completing menial tasks like giving yourself a gold star for completing all your paperwork. Gamification can also be done through more complex, corporate sponsored projects. To us, Gamification should be implemented without having to offer material incentives to change a person’s behavior. Over the past few months three attempts were made on the WPI campus to demonstrate this non-incentivized Gamification. The three experiments – “The Minefield”, “Battery Recycling Bin”, and “Trashketball” – brought about a variety of reactions from the students, faculty, and staff where apparent interest and amusement were observed

Geotechnical Observations of the November 3, 2002 M7.9 Denali Fault Earthquake

The M 7.9 earthquake of November 3, 2002 event ruptured more than 340 kilometers on three fault, causing widespread liquefaction in the fluvial deposits of steep alpine valleys of the Alaska Range and eastern lowlands of the Tanana River. The event occurred in a remote and largely undeveloped portion of the rugged Alaskan central range, with few seismometer recordings. The areas affected by liquefaction are largely confined to native Holocene river deposits, areas bounded by stiffer ground moraine, Pleistocene uplands, and bedrock. Liquefaction affected areas of alluvial river valleys draining mountainous and glacier-proximal rivers. The most noteworthy observations are that liquefaction damage was focused towards the eastern end of the rupture area. In the western portion of the rupture zone, localized liquefaction developed in recent deposits of the Susitna and Delta rivers in the immediate vicinity of the surface rupture of the fault. More abundant and severe liquefaction occurred on the eastern Robertson, Slana, Tok, Chisana and, especially, Nabesna Rivers. In the Tanana lowland, liquefaction features were sparse on the western bars of the Tanana River in the vicinity of Fairbanks to west of Delta, but became pervasive throughout the eastern region from Delta to Northway. Though liquefaction observations were abundant, there was a dearth of instrumental recordings useful to relate damage effects to measured intensity. To characterize soil properties and stiffness of liquefaction evaluation sites, we used a portable spectral analysis of surface waves (SASW) apparatus to profile the shear wave velocity of the ground. On the Nabesna and Delta rivers that cross the fault, we only observe liquefaction features in soil deposits where normalized shear wave velocities fall below 230 m/s. Severity of sand boils, fissuring and lateral displacement of liquefied ground dramatically increase in soils of lower shear wave velocity, especially below 170 m/s. Some of the most pronounced ground failures are far from the fault zone (60-100 km) in extremely loose, low velocity (~120 m/s) fine sands of the bars of the Tanana River. Strong motion instrumentation was sparse within 150 kilometers of the fault rupture and the seismometers of Alyeska pump stations PS9 (PGA=0.09), PS10 (PGA=0.36g), and PS11 (PGA=0.09) serve as the principal strong motion recordings. Insufficient strong motion instrumentation is available to identify areas of amplified ground motio

Evryscope Science: Exploring the Potential of All-Sky Gigapixel-Scale Telescopes

Low-cost mass-produced sensors and optics have recently made it feasible to build telescope arrays which observe the entire accessible sky simultaneously. In this article, we discuss the scientific motivation for these telescopes, including exoplanets, stellar variability, and extragalactic transients. To provide a concrete example we detail the goals and expectations for the Evryscope, an under-construction 780 MPix telescope which covers 8660 sq. deg. in each 2-minute exposure; each night, 18,400 sq. deg. will be continuously observed for an average of ≈6 hr. Despite its small 61 mm aperture, the system's large field of view provides an étendue which is ∼10% of LSST. The Evryscope, which places 27 separate individual telescopes into a common mount which tracks the entire accessible sky with only one moving part, will return 1%-precision, many-year-length, high-cadence light curves for every accessible star brighter than ∼16th magnitude. The camera readout times are short enough to provide near-continuous observing, with a 97% survey time efficiency. The array telescope will be capable of detecting transiting exoplanets around every solar-type star brighter than mV = 12, providing at least few-millimagnitude photometric precision in long-term light curves. It will be capable of searching for transiting giant planets around the brightest and most nearby stars, where the planets are much easier to characterize; it will also search for small planets nearby M-dwarfs, for planetary occultations of white dwarfs, and will perform comprehensive nearby microlensing and eclipse-timing searches for exoplanets inaccessible to other planet-finding methods. The Evryscope will also provide comprehensive monitoring of outbursting young stars, white dwarf activity, and stellar activity of all types, along with finding a large sample of very-long-period M-dwarf eclipsing binaries. When relatively rare transients events occur, such as gamma-ray bursts (GRBs), nearby supernovae, or even gravitational wave detections from the Advanced LIGO/Virgo network, the array will return minute-by-minute light curves without needing pointing toward the event as it occurs. By coadding images, the system will reach V ∼ 19 in 1-hr integrations, enabling the monitoring of faint objects. Finally, by recording all data, the Evryscope will be able to provide pre-event imaging at 2-minute cadence for bright transients and variable objects, enabling the first high-cadence searches for optical variability before, during and after all-sky events

Preliminary Report on the Seismological and Engineering Aspects of the January 17, 1994 Northridge Earthquake

This report on the seismological and engineering aspects of the 17 January, 1994, Northridge earthquake was printed on 24 January, 1994, one week after the main event. Its purpose is to provide a brief overview of preliminary observations related to the earthquake. The primary audience is seismologists, engineers and related professionals in the earthquake hazard and earthquake risk mitigation field. The report is preliminary in the sense that significant data collection and analysis remain to be completed. Reports containing more complete data and analysis may be issued at a later date. Immediately following the 17 January, 1994, Northridge earthquake, the Earthquake Engineering Research Center dispatched a reconnaissance team to the epicentral region. This report, issued one week after the earthquake, provides an overview of the seismological and engineering aspects of the earthquake and associated aftershocks. A slide set containing approximately 1 00 slides obtained during the reconnaissance, including all slides and photographs in this report, is being prepared. Copies of the set are available at cost. To obtain a set, write to EERC Reports, 1301 S. 46th Street, Richmond, California 94804, e-mail to [email protected], call510-231-9468, or fax 510-231-9461.National Science Foundation///Virginia, Estados UnidosUCR::Vicerrectoría de Docencia::Ingeniería::Facultad de Ingeniería::Escuela de Ingeniería Civi

Cyclooxygenases and the cardiovascular system.

Cyclooxygenase (COX)-1 and COX-2 are centrally important enzymes within the cardiovascular system with a range of diverse, sometimes opposing, functions. Through the production of thromboxane, COX in platelets is a pro-thrombotic enzyme. By contrast, through the production of prostacyclin, COX in endothelial cells is antithrombotic and in the kidney regulates renal function and blood pressure. Drug inhibition of COX within the cardiovascular system is important for both therapeutic intervention with low dose aspirin and for the manifestation of side effects caused by nonsteroidal anti-inflammatory drugs. This review focuses on the role that COX enzymes and drugs that act on COX pathways have within the cardiovascular system and provides an in-depth resource covering COX biology and pharmacology. The review goes on to consider the role of COX in both discrete cardiovascular locations and in associated organs that contribute to cardiovascular health. We discuss the importance of, and strategies to manipulate the thromboxane: prostacyclin balance. Finally within this review the authors discuss testable COX-2-hypotheses intended to stimulate debate and facilitate future research and therapeutic opportunities within the field

Influence of faults on groundwater flow and transport at Yucca Mountain, Nevada

Numerical simulations of groundwater flow at Yucca Mountain, Nevada are used to investigate how faults influence groundwater flow pathways and regional-scale macrodispersion. The 3-D model has a unique grid block discretization that facilitates the accurate representation of the complex geologic structure present in faulted formations. Each hydrogeologic layer is discretized into a single layer of irregular and dipping grid blocks, and faults are discretized such that they are laterally continuous and varied in displacement varies along strike. In addition, the presence of altered fault zones is explicitly modeled, as appropriate. Simulations show that upward head gradients can be readily explained by the geometry of hydrogeologic layers, the variability of layer permeabilities, and the presence of permeable fault zones or faults with displacement only, not necessarily by upwelling from a deep aquifer. Large-scale macrodispersion results from the vertical and lateral diversion of flow near the contact of high- and low-permeability layers at faults, and from upward flow within high-permeability fault zones. Conversely, large-scale channeling can occur as a result of groundwater flow into areas with minimal fault displacement. Contaminants originating at the water table can flow in a direction significantly different from that of the water table gradient, and isolated zones of contaminants can occur at the water table downgradient. By conducting both 2-D and 3-D simulations, we show that the 2-D cross-sectional models traditionally used to examine flow in faulted formations may not be appropriate. In addition, the influence of a particular type of fault cannot be generalized; depending on the location where contaminants enter the saturated zone, faults may either enhance or inhibit vertical dispersion

First-Order Reliability Analysis of Groundwater Flow

A method for stochastic analysis of groundwater flow based on the first-order reliability approach is presented. The method is well suited for problems in which statistical information is limited to second moments and marginal distributions, as is commonly the case for groundwater flow analyses. A stochastic finite element model is described which utilizes the first-order reliability approach to estimate probabilities associated with a particular performance criterion for confined or unconfined saturated groundwater flow in porous media. Element hydraulic conductivities and boundary conditions are assumed to be random variables with known second moments and marginal distributions. The model estimates the probability of exceeding a specified target fluid flux or nodal fluid head, and provides sensitivity information